Entries from Jürgen

Parkinson's research needs private donations

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Japanese scientists have developed a new blood test that can detect Parkinson's with high accuracy.

The test works by detecting a specific protein called α-synuclein that is misfolded in these diseases.

Previous tests could also detect this protein, but they required an invasive method that involved taking a sample from the spinal cord (cerebrospinal fluid). This new test can detect the protein directly in the blood, making it much easier and less invasive.

Parkinson's and skin cancer

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The increased risk of melanoma in Parkinson's patients has been documented in numerous scientific studies. A first comprehensive meta-analysis was published by Liu and colleagues in the journal Neurology in 2011 and found that people with Parkinson's had more than double the risk of being diagnosed with melanoma. An important study on this topic was also published in 2010 by John Bertoni and colleagues in the Archives of Neurology (later renamed JAMA Neurology). The Bertoni study used data from the North American Parkinson's and Melanoma Survey Group and found that the incidence of malignant melanoma was 2,24 times higher in the Parkinson's cohort compared to the general population.

Legal aspects of Parkinson's, severe disability

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I. Legal bases
The term "severe disability" is defined in Section 2, Paragraph 1, Clause 1 of the
Social Code Book IX legally defined:
“People with disabilities are people who have physical, mental, spiritual
or have sensory impairments that interact with attitudinal and
environmental barriers to equal participation in society
high probability for longer than six months".
Section 2, paragraph 2 of the Social Security Code IX defines when a severe disability
exists:
1
As of June 24, 2020
This is a guide that has been created to the best of our knowledge.
However, he does not claim to be completely correct and
Completeness. Any liability is excluded.
"People are severely disabled within the meaning of Part 3 (SGB IX) if they
a degree of disability of at least 50 and their place of residence, their
habitual residence or their employment in a workplace within the meaning of
§ 156 lawfully have within the scope of this code."
And § 2 para. 2 of the Social Security Code IX stipulates for equality:
“People with severe disabilities should be given equal treatment
Disabilities with a degree of disability less than 50, but at least
30, in which the other requirements of paragraph 2 are met if they result
their disability a suitable job within the meaning of the
Section 156 cannot be obtained or retained (disabled persons with equal status
People)."

Neuro-centered training in everyday life: theme of balance

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The sense of balance, also called the vestibular system, is an important part of the human body. It ensures that we control our posture and movements and orientate ourselves in space. The vestibular system works closely with other sensory organs, such as the eyes and brain, to form a complex network of information that enables us to move safely in our environment.

medication planner

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Why is it so important to stick to mealtimes in people with Parkinson's disease?

1. Drug Interaction:

Many Parkinson's patients take levodopa, which works best on an empty stomach. Protein-rich foods can compete with the absorption of levodopa in the gut, which can lead to a reduced effect of the drug. Therefore, it is often recommended that levodopa be taken at least 30 minutes before a meal or at least 60 minutes after a meal

Optimized therapy for late motor complications in advanced Parkinson's disease

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The Therapy of movement disorders in the advanced stages of idiopathic Parkinson's disease represents a challenge because optimizing dopamine treatment does not always produce the expected results. It is therefore crucial to consider more intensive treatment approaches in a timely manner. As soon as signs of an advanced stage become apparent, doctors should immediately inform patients about suitable treatment options and familiarize patients with possible treatment options.

The Parkinson-Bot – artificial intelligence now also in the Parkinson Journal

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In the circle of the authors and with many acquaintances and friends, whether affected by Parkinson's or not, I discussed for a long time whether we should integrate ChatGPT as a bot into our Parkinsonal Journal. 

Last but not least, we asked the "Parkinson-Bot" itself about the usefulness and it is amazing how much it reflects the different opinions from the circle mentioned above.

In the following you can read my discussion with the artificial intelligence and form your own opinion. The chat is reproduced here one to one, without any editing

New blood test for early detection of Parkinson's disease

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Japanese scientists have developed a new blood test that can detect Parkinson's with high accuracy.

The test works by detecting a specific protein called α-synuclein that is misfolded in these diseases.

Previous tests could also detect this protein, but they required an invasive method that involved taking a sample from the spinal cord (cerebrospinal fluid). This new test can detect the protein directly in the blood, making it much easier and less invasive.