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7 Search results for: gastrointestinal

1

Gastrointestinal symptoms in Parkinson's disease and their causes

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There is hardly a Parkinson's patient who does not know them: The gastrointestinal complaints, i.e. those affecting the gastrointestinal tract. 

These include

Dysphagia = swallowing disorders
Sialorrhea = the involuntary discharge of saliva from the mouth
Gastroparesis = Stomach paralysis or delayed emptying of the stomach
Constipation = constipation

The symptoms appear years to decades before the onset of the motor symptoms.

Gastroparesis occurs in seventy to one hundred percent of patients. According to PD Dr. Lisa Klingelhöfer from the Clinic for Neurology at the University Hospital Dresden, a clear connection with the severity of the motor symptoms. The consequences are usually weight loss, malnutrition and dehydration. To make matters worse, in the case of disturbed peristalsis and absorption, a delayed or, in the worst case, no effect of the oral Parkinson's medication is to be expected.

2

Stomach, intestines, exercise and Parkinson's disease

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Mrs. Prof. Dr. Brit Mollenhauer on the current state of research:

The research focuses on alpha-synuclein, whose pathological aggregation in the nerve cells due to protein misfolding has been identified as the main cause of Parkinson's. Three strategies are being examined here: inhibiting the build-up, promoting the breakdown and preventing the transfer to the neighboring cells, so to speak their contagion.

4

New insights into intestinal health and Parkinson's

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Influence of intestinal health on Parkinson's and MS: New findings from the University Medical Center Magdeburg

The importance of gut health to the human body goes far beyond digestion. Researchers at the University Medical Center Magdeburg have discovered that the intestinal microbiome can have a decisive influence on the development of chronic inflammatory and neurodegenerative diseases such as multiple sclerosis (MS) and Parkinson's. This article presents the latest findings from the research group “Translational Neuroimmunology and Neurodegeneration” led by Prof. Dr. med. Aiden Haghikia described in more detail.

7

medication planner

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Why is it so important to stick to mealtimes in people with Parkinson's disease?

1. Drug Interaction:

Many Parkinson's patients take levodopa, which works best on an empty stomach. Protein-rich foods can compete with the absorption of levodopa in the gut, which can lead to a reduced effect of the drug. Therefore, it is often recommended that levodopa be taken at least 30 minutes before a meal or at least 60 minutes after a meal