New medical guidelines for Parkinson's disease

A new medical guideline on Parkinson's has been available for a few days now.

But what is a medical guideline and how and where is it used?

A medical guideline is a documented procedure for diagnostics and therapy in specific medical areas.

It is based on current scientific findings and clinical experience and serves to ensure and improve the quality of patient care.

Guidelines provide recommendations on how to approach specific diseases or conditions to achieve the best patient outcome.

They are created by professional societies or other medical organizations and are often an important source of information and decision-making aid for doctors and medical staff.

Cell therapies and what you need to know about them

Cell therapy is a revolutionary medical technique that aims to treat disease or injury at the cellular level. This approach has the potential to eclipse traditional therapies that focus primarily on symptom relief.

Advantages of cell therapy:

Targeted Treatment: Unlike traditional therapies, which often affect the entire body, cell therapy can directly target the affected tissue or organ, which can minimize side effects.
Potential for permanent cure: Rather than just treating symptoms, cell therapy aims to address the cause of the disease. This means it has the potential to provide permanent or long-lasting cures.
Use of the body's own cells: In many cases, the patient's cells are used, which reduces the risk of rejection or incompatibilities.

Human Brain Project is over!

The Human Brain Project (HBP) was an ambitious scientific endeavor focused on recreating the human brain in a digital way. This ten-year project, funded by the European Union, brought together over 500 researchers from different disciplines and countries with the common goal of better understanding and digitalizing the complex network of almost 100 billion nerve cells and the millions of kilometers of nerve fibers that connect them to recreate.

New insights into intestinal health and Parkinson's

Influence of intestinal health on Parkinson's and MS: New findings from the University Medical Center Magdeburg

The importance of gut health to the human body goes far beyond digestion. Researchers at the University Medical Center Magdeburg have discovered that the intestinal microbiome can have a decisive influence on the development of chronic inflammatory and neurodegenerative diseases such as multiple sclerosis (MS) and Parkinson's. This article presents the latest findings from the research group “Translational Neuroimmunology and Neurodegeneration” led by Prof. Dr. med. Aiden Haghikia described in more detail.

Neuroplasticity and its importance in Parkinson's disease

It's amazing how adaptable our brains really are. Previous assumptions that the brain is unchanging after birth have been refuted. Neuroplasticity, the brain's ability to reorganize and adapt, opens new doors in medical research and treatment, particularly in diseases such as Parkinson's.

LSVT BIG ©, part 2

LSVT BIG was developed to counteract the movement problems typical of Parkinson's, such as stiffness, tremors and slowness. While we dealt with the basics in the first part, we look at the therapeutic process in the second part.

Skin biopsies and DATscan in focus

In recent years, the diagnosis of Parkinson's disease and similar neurodegenerative diseases has made significant progress. New diagnostic procedures such as skin biopsies and DaTscans have attracted the attention of researchers and medical professionals. But when are these tests really necessary, and what can they tell us about Parkinson's? In this article, we will address these questions and examine the role of these innovative diagnostic methods in more detail.

The core message:
The use of skin biopsies and DaTscans to diagnose Parkinson's is not necessary in all cases but should be carefully decided on an individual basis.

Gene mutations and deep brain stimulation

Now the effects of GBA mutations on the long-term outcome of deep brain stimulation in Parkinson's disease have been examined in a study with 296 participants. It was found that patients with GBA variants became ill at a younger age, had a shorter duration of illness before deep brain stimulation and had more frequent dyskinesias. After 3 to 5 years, both groups showed improvement in motor symptoms and satisfactory control of fluctuations and dyskinesias. Non-motor symptoms were comparable, except for cognition, which deteriorated more rapidly in GBA Parkinson's patients. Analysis by the exact GBA mutation type is ongoing, but preliminary data suggests that GBA Parkinson's patients benefit from deep brain stimulation just as much as patients without GBA variants.

New hope for Parkinson's patients through stem cell technology?

The increased risk of melanoma in Parkinson's patients has been documented in numerous scientific studies. A first comprehensive meta-analysis was published by Liu and colleagues in the journal Neurology in 2011 and found that people with Parkinson's had more than double the risk of being diagnosed with melanoma. An important study on this topic was also published in 2010 by John Bertoni and colleagues in the Archives of Neurology (later renamed JAMA Neurology). The Bertoni study used data from the North American Parkinson's and Melanoma Survey Group and found that the incidence of malignant melanoma was 2,24 times higher in the Parkinson's cohort compared to the general population.

When diet becomes a compulsion

The increased risk of melanoma in Parkinson's patients has been documented in numerous scientific studies. A first comprehensive meta-analysis was published by Liu and colleagues in the journal Neurology in 2011 and found that people with Parkinson's had more than double the risk of being diagnosed with melanoma. An important study on this topic was also published in 2010 by John Bertoni and colleagues in the Archives of Neurology (later renamed JAMA Neurology). The Bertoni study used data from the North American Parkinson's and Melanoma Survey Group and found that the incidence of malignant melanoma was 2,24 times higher in the Parkinson's cohort compared to the general population.